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上海中医药杂志:2015,49(6):81-84
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清肺止咳灵糖浆对慢性支气管炎急性发作期止咳祛痰平喘作用的实验研究
田伟1,张淑香2,江柏华3
(1.黑龙江中医药大学附属第一医院重点学科专科办公室(黑龙江哈尔滨150040);2.黑龙江中医药大学中医药研究院药理室(黑龙江哈尔滨150040);3.黑龙江省中医医院呼吸科(黑龙江哈尔滨150036 ))
Antitussive, apophlegmatic and antiasthmatic effects of “Qingfei Zhikeling Syrup” on acute attack of chronic bronchitis
TIAN Wei1, ZHANG Shu-xiang2, JIANG Bai-hua3
(1.The First Hospital Affiliated to Heilongjiang University of Traditional Chinese Medicine;2.Academy of Traditional Chinese Medicine of Heilongjiang University of Chinese Medicine;3.Heilongjiang Provincical Hospital of Traditional Chinese Medicine)
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中文摘要:   目的:研究清肺止咳灵糖浆对慢性支气管炎急性发作期的止咳祛痰平喘作用  方法:通过对SO2致小鼠咳嗽、毛细玻管法测大鼠排痰量、豚鼠磷酸组胺喷雾引喘潜伏期的观察,研究清肺止咳灵糖浆对慢性支气管炎急性发作期的止咳祛痰平喘作用  结果:清肺止咳灵糖浆能明显延长小鼠对SO2刺激引起咳嗽的潜伏期(P<0.05),能显著增加大鼠气管排痰量(P<0.05),能明显延长豚鼠磷酸组胺喷雾引喘潜伏期(P<0.05)  结论:清肺止咳灵糖浆对慢性支气管炎急性发作期具有明显的止咳祛痰平喘作用。
Abstract:  Objective:This paper is to research antitussive, apophlegmatic and antiasthmatic effects of “Qingfei Zhikeling Syrup” on chronic bronchitis acute attack  Methods:Thre  Methods: were used in this experiment include the observation of cough that was induced by SO2 in mice, observation on the phlegm expelling in rats by using glass capillary and the observation of incubation period of guinea pig induced by histamine phosphate  Results:“Qingfeizhikeling Syrup” can significantly prolong the mice to SO2 stimulation caused cough incubation period (P<0.05), can significantly increase the rat trachea sputum volume(P<0.05), can obviously prolong the guinea pig histamine phosphate spray out of the incubation period(P<0.05)  Conclusion:“Qingfeizhikeling Syrup” of chronic bronchitis acute phase has obvious Antitussive, apophlegmatic and anti-asthmatic effect.
文章编号:20150629     中图分类号:    文献标志码:
基金项目:黑龙江省中医药管理局青年基金项目(黑20070469)
引用文本:
田伟,张淑香,江柏华.清肺止咳灵糖浆对慢性支气管炎急性发作期止咳祛痰平喘作用的实验研究[J].上海中医药杂志,2015,49(6):81-84.
TIAN Wei,ZHANG Shu-xiang,JIANG Bai-hua.Antitussive, apophlegmatic and antiasthmatic effects of “Qingfei Zhikeling Syrup” on acute attack of chronic bronchitis[J].Shanghai J Tradit Chin Med,2015,49(6):81-84.