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DOI:
:2018,32(3):12-16
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中医对围绝经期综合征的认识与治疗
范振宇,杨娟
(上海中医药大学药物临床研究中心(上海201203))
Cognition and treatment of perimenopausal syndrome by traditional Chinese medicine
FAN Zhenyu,YANG Juan
(Drug Clinical Research Center,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
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中文摘要: 中医学认为,肾、肝、脾、心诸脏功能失调是围绝经期综合征的发病基础,而肾中精气不足、机体阴阳失调、脏腑功能紊乱是根本病机。辨证主要主张以肝肾阴虚、肾阳亏虚分型,也兼见各家之见;治疗多从辨证论治,亦有基本方加减或中成药治疗,以及针灸,或配合心理治疗等,临床表明对改善卵巢功能、改善伴随症状有可靠的疗效,且无明显副作用,但缺少公认的临床疗效指南和治疗指针。因此,在中医治疗规范化方面尚待重视,另外某些中药或单体也具有植物雌激素或非植物雌激素药物作用,为中医药的开发和应用提供了广阔的前景。
Abstract:In traditional Chinese medicine,it is considered that the dysfunction of kidney,liver,spleen and heart is the basis of perimenopausal syndrome,and the insufficiency of kidney essence,the imbalance of yin and yang and the dysfunction of zang-fu viscera are the fundamental pathogenesis. The syndrome differentiation is mainly based on yin deficiency of liver and kidney and deficiency of kidney yang,which combined with views of different doctors. The treatments are mainly performed according to syndrome differentiation,and there are also basic prescriptions with modification or traditional Chinese patent medicines and simple preparations,acupuncture,or psychotherapy. It has proved that these therapies show the reliable efficacy on improving the ovarian function and accompanying symptoms,without obvious side effects,but it lacks commonly recognized clinical efficacy guidelines and therapeutic indications. Therefore,the standardization of traditional Chinese medicine treatment still needs to be paid attention. In addition,some Chinese medicine or monomers also show phytoestrogen or non-phytoestrogen effects,which would provide a broad prospect for the development and application of traditional Chinese medicine.
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基金项目:上海科技创新行动计划项目(17401970900) [
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